Mitochondrial Genome Analyses and Haplo-Group Determination in Human Skeletons

Abstract

Molecular anthropology has been dramatically enhanced recently by the development of highthroughput next generation sequencing. Significant datas have been obtained in respects of biocultural evolution of human under favour of ancient DNA researches in recent years. In Turkey, even if giving consequence to this field has been increased for five years, it is still limited. In this study, d-loop region of mitochondrial DNA extracted from human skeletons which uncovered from Nif Mountain Excavations in İzmir, Turkey was sequenced and haplo-groups were determined. Then, it was aimed to set down migration patterns using bioinformatic tools. In-depth information about Western Anatolia was revealed by evaluating this datas with archeological findings. This study has importance to pave the way of ancient DNA researches that is going to conduct in the future in Turkey. Information was got from this study has qualification to be a source future researches from archeological excavations of Western Anatolia. This thesis that bears archeological and historical records out has also a potential to lead to interdiciplinary fields.